N,N-Dimethylaniline → Carbofuran

HRID 4429

Reaction equation

HRID 4429 reaction equation
[C:1](=O)([O:6][C:7]1[C:15]2[O:14][C:13]([CH3:17])([CH3:16])[CH2:12][C:11]=2[CH:10]=[CH:9][CH:8]=1)[O:2]C(Cl)C.[CH3:19][N:20](C)C1C=CC=CC=1>N1C=CC=CC=1>[CH3:19][NH:20][C:1](=[O:2])[O:6][C:7]1[C:15]2[O:14][C:13]([CH3:17])([CH3:16])[CH2:12][C:11]=2[CH:10]=[CH:9][CH:8]=1

Participants

4

Reactant 2

HCID 949N,N-DimethylanilineHCID 135570951-Chloroethyl 2,3-dihydro-2,2-dimethyl-7-benzofuranyl carbonate

Product 1

HCID 2566Carbofuran

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

The procedure is as in (a) followed by (b), but pyridine is replaced by N,N-dimethylaniline and the intermediate carbonate is not distilled. Starting with 16.4 g of 2,3-dihydro-2,2-dimethyl-7-benzofuranol, 16.8 g (76%) of CARBOFURAN are then obtained, M.p. 147° C.

Workup

  1. distillationthe intermediate carbonate is not distilled
  2. customare then obtained

Sources & evidence

ORD record
ord-d4106ac42a79474482487a508c64ea90
Source dataset
uspto-grants-1988_02
Patent number
US04725680

Linked notes

Loading…