HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 44293Generated: October 24, 2026
Ethanolamine → 2-[2-(4-Nitro-phenyl)-ethylamino]-ethanol
https://huagongshe.com/en/reaction/44293
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethanolamine | HCID 700 | — |
| Reactant | 4-Nitrophenethyl bromide | HCID 79266 | — |
| Product | 2-[2-(4-Nitro-phenyl)-ethylamino]-ethanol | HCID 22722744 | — |
Reaction Steps
A mixture of 1-(2-bromo-ethyl)-4-nitro-benzene (86.9 mmoles) and 2-amino-ethanol (869 mmoles) is heated at 150° C. under microwave activation for 10 minutes. The reaction mixture is evaporated to dryness and the residue obtained is purified on silica gel (SiO2; gradient DCM/MeOH) to yield the title product, which is used directly in the next Step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08541412B2 |
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| Source dataset | uspto-grants-2013_09 |
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| ORD ID | ord-2b4fbf189855456f819977f42058ce7e |
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| Source note | uspto-grants-2013_09 |
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