Chloroacetyl chloride → HCID 23467572, compound

Reaction equation

[F:1][C:2]1[CH:3]=[C:4]([C:8]2[N:13]=[N:12][C:11]([NH:14][NH2:15])=[CH:10][CH:9]=2)[CH:5]=[CH:6][CH:7]=1.[Cl:16][CH2:17][C:18](Cl)=O>>[Cl:16][CH2:17][C:18]1[N:12]2[N:13]=[C:8]([C:4]3[CH:5]=[CH:6][CH:7]=[C:2]([F:1])[CH:3]=3)[CH:9]=[CH:10][C:11]2=[N:14][N:15]=1

Participants

Reactant 2

HCID 6577Chloroacetyl chloride

HCID 234675683-(3-Fluorophenyl)-6-hydrazinylpyridazine

Product 1

HCID 23467572HCID 23467572, compound

Procedure

As for Example 2, 6-(3-fluorophenyl)-3-hydrazinopyridazine (prepared in a manner similar to that described in Example 1) is reacted with chloroacetyl chloride to give the product of the Example.

Workup

customto give the product of the Example

Sources & evidence

ORD record: ord-1dd3d22d6ac44fe1b4ade8dffe0703df
Source dataset: uspto-grants-1981_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04260755

Reaction notes

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