HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyanic acid → 5-(6-Ethoxycarbonylhexyl)-1-(3-cyclohexyl-3-oxopropyl)hydantoin
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyanic acid | HCID 540 | — |
| Reactant | Diethyl 2-[(3-cyclohexyl-3-oxopropyl)amino]nonanedioate | HCID 3017622 | — |
| Product | 5-(6-Ethoxycarbonylhexyl)-1-(3-cyclohexyl-3-oxopropyl)hydantoin | HCID 20436903 | — |
Reaction Steps
Reaction of diethyl 2-((3-cyclohexyl-3-oxopropyl)amino)nonanedioate (20.8 g) with cyanic acid using the general procedure of Example 2d afforded 5-(6-ethoxycarbonylhexyl)-1-(3-cyclohexyl-3-oxopropyl)hydantoin which was converted to the corresponding acid which crystallised from ether, m.p. 77.5°-78.5° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04262128 |
| Source dataset | uspto-grants-1981_04 |
| ORD ID | ord-ae1f242a9584414e9c067da8f621213a |
| Source note | uspto-grants-1981_04 |