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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 445133Generated: October 26, 2026

4-Methylbenzaldehyde → N-(1H-indazol-5-yl)-2-(4-methylbenzyl)-2-azabicyclo[2.2.2]octan-4-amine

https://huagongshe.com/reaction/445133

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethylbenzaldehydeHCID 7725—
ReactantN-(1H-indazol-5-yl)-2-azabicyclo[2.2.2]octan-4-amineHCID 67234936—
ProductN-(1H-indazol-5-yl)-2-(4-methylbenzyl)-2-azabicyclo[2.2.2]octan-4-amineHCID 53247678—

Reaction Steps

Reaction of Intermediate 26 with 4-methylbenzaldehyde affords the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08476295B2
Source datasetuspto-grants-2013_07
ORD IDord-5fa135ffb5f94c318cfa248020eb1208
Source noteuspto-grants-2013_07