Pentanamide → 2-Butyl-4-thiazolecarboxylic acid
Reaction equation
CC[CH:3]([C:6]1[S:7][CH:8]=[C:9]([C:11]([O:13]CC)=[O:12])[N:10]=1)[CH2:4][CH3:5].[C:16](N)(=O)CCCC>>[CH2:3]([C:6]1[S:7][CH:8]=[C:9]([C:11]([OH:13])=[O:12])[N:10]=1)[CH2:4][CH2:5][CH3:16]Participants
3
Procedure
Prepared by the method of Carboxylic Acid 3, from step b using pentanamide (10 g) in place of 2-ethylbutanamide in step b. Yield 4.6 g.
Sources & evidence
- ORD record
- ord-b4a66fa25de242c89aa2c15d477a3279
- Source dataset
- uspto-grants-2013_07
- Patent number
- US08476265B2
Reaction notes
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