HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 3-((1-Methylpiperidin-4-yl)oxy)aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | N-[3-(1-Methyl-piperidin-4-yloxy)-phenyl]-acetamide | HCID 57444159 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 3-((1-Methylpiperidin-4-yl)oxy)aniline | HCID 39202654 | — |
Reaction Steps
A solution of N-[3-(1-Methyl-piperidin-4-yloxy)-phenyl]-acetamide (2.604 g) in absolute ethanol (40 mL) was treated with 37% hydrochloric acid and the solution was heated to reflux for 3 hours.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08541429B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-6031bf9140c847b7b1fab5f57e68279e |
| Source note | uspto-grants-2013_09 |