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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 4468Generated: October 26, 2026

7-bromo-2,3-dihydro-1H-indol-2-one → 6-Chloro-1,3-dihydroindol-2-one

https://huagongshe.com/reaction/4468

Reaction equation

Participants

RoleNameHCIDCharge
Reactant7-bromo-2,3-dihydro-1H-indol-2-oneHCID 2773291—
Reactant5,7-difluoro-1,3-dihydro-2H-indol-2-oneHCID 2778963—
Reactant2H-Indol-2-one, 1,3-dihydro-7-methyl-HCID 3014225—
Reactant7-Fluoro-2,3-dihydro-1h-indol-2-oneHCID 3734371—
Reactant7-CyclohexyloxindoleHCID 21282019—
Reactant4,6-DifluorooxindoleHCID 21282037—
Reactant7-CyclopropyloxindoleHCID 21282066—
Reactant4,7-Dichloro-1,3-dihydro-2H-indol-2-oneHCID 21282084—
Reactant5-n-Butyl-7-fluorooxindoleHCID 21282093—
Product6-Chloro-1,3-dihydroindol-2-oneHCID 736344—

Reaction Steps

In an analogous manner 4- and 6-fluoro- and bromooxindoles are prepared, as well as 7-fluorooxindole, 7-bromooxindole, 7-methyloxindole, 4,6-difluorooxindole, 4,7-dichlorooxindole, 5,7-difluorooxindole, 5-n-butyl-7-fluorooxindole, 7-cyclohexyloxindole and 7-cyclopropyloxindole.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04725616
Source datasetuspto-grants-1988_02
ORD IDord-fb27c21061f54078be4fc125c2783746
Source noteuspto-grants-1988_02