Phenyl carbamate → 4-Methyl-3-(1-methyl-1H-pyrazolo[3,4-c]pyridin-4-ylethynyl)-phenylamine

HRID 446927

Reaction equation

[CH3:1][N:2]1[C:6]2=[CH:7][N:8]=[CH:9][C:10]([C:11]#[C:12][C:13]3[CH:14]=[C:15]([NH2:19])[CH:16]=[CH:17][CH:18]=3)=[C:5]2[CH:4]=[N:3]1.[C:20](=O)(OC1C=CC=CC=1)N>>[CH3:20][C:18]1[CH:17]=[CH:16][C:15]([NH2:19])=[CH:14][C:13]=1[C:12]#[C:11][C:10]1[CH:9]=[N:8][CH:7]=[C:6]2[N:2]([CH3:1])[N:3]=[CH:4][C:5]=12

Participants

Reactant 2

HCID 69322Phenyl carbamate

HCID 595364393-(1-Methyl-1H-pyrazolo[3,4-c]pyridin-4-ylethynyl)-phenylamine2×

Product 1

HCID 595364374-Methyl-3-(1-methyl-1H-pyrazolo[3,4-c]pyridin-4-ylethynyl)-phenylamine

Procedure

The following example compound 3.2 was synthesized in analogy to GP 7 and example compound 3.1 by reaction of Intermediate 3.1 with the respective phenyl carbamate.

Sources & evidence

ORD record: ord-307c9b40d1f64771a8d1b8184c8863f2
Source dataset: uspto-grants-2013_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08481539B2

Linked notes

Loading…