2-Chloro-4-(2-(trimethylsilyl)ethynyl)pyridine → HCID 86595323, compound

HRID 447210

Reaction equation

HRID 447210 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([C:8]#[C:9][Si](C)(C)C)[CH:5]=[CH:4][N:3]=1.[Cl:14][C:15]1[CH:20]=[CH:19][C:18]([N:21]2[CH:25]=[C:24](I)[N:23]=[C:22]2[CH:27]([CH3:29])[CH3:28])=[CH:17][N:16]=1>>[Cl:1][C:2]1[CH:7]=[C:6]([C:8]#[C:9][C:24]2[N:23]=[C:22]([CH:27]([CH3:29])[CH3:28])[N:21]([C:18]3[CH:17]=[N:16][C:15]([Cl:14])=[CH:20][CH:19]=3)[CH:25]=2)[CH:5]=[CH:4][N:3]=1

Participants

3

Reactant 2

HCID 219853912-Chloro-4-(2-(trimethylsilyl)ethynyl)pyridineHCID 86012438HCID 86012438, compound

Product 1

HCID 86595323HCID 86595323, compound

Procedure

The title compound, MS: m/e=358.1 (M+H+), was prepared in accordance with the general method of example B, step 2, from 2-Chloro-4-trimethylsilanylethynyl-pyridine and 2-Chloro-5-(4-iodo-2-isopropyl-imidazol-1-yl)-pyridine.

Sources & evidence

ORD record
ord-2dd5098c0f674dca9257a19fa7585a35
Source dataset
uspto-grants-2013_07
Patent number
US08481548B2

Linked notes

Loading…