4-Butylamino-1-cyclohexyloxy-2,2,6,6-tetramethylpiperidine → 1-Cyclohexyloxy-2,2,6,6-tetramethyl-1,2,3,6-tetrahydro-pyridine

HRID 448534

Reaction equation

HRID 448534 reaction equation

C(N[CH:6]1[CH2:11][C:10]([CH3:13])([CH3:12])[N:9]([O:14][CH:15]2[CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]2)[C:8]([CH3:22])([CH3:21])[CH2:7]1)CCC>[Pd].CO>[CH:15]1([O:14][N:9]2[C:8]([CH3:22])([CH3:21])[CH:7]=[CH:6][CH2:11][C:10]2([CH3:13])[CH3:12])[CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]1

Participants

4

Reactant 1

HCID 211821294-Butylamino-1-cyclohexyloxy-2,2,6,6-tetramethylpiperidine

Product 1

HCID 574651861-Cyclohexyloxy-2,2,6,6-tetramethyl-1,2,3,6-tetrahydro-pyridine

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalyst

HCID 887MethanolSolvent

Procedure

Hydrogenation at this stage (MeOH, 5% Pd/C, 5 bar H2, 40° C.) leads to butyl-(1-cyclohexyloxy-2,2,6,6-tetramethyl-piperidin-4-yl)-amine, compound D.

Sources & evidence

ORD record: ord-043308aa0dd744cb9cb7c7cf7e004136
Source dataset: uspto-grants-2013_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08481726B2

Linked notes

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