(2-(4-Bromophenoxy)ethyl)dimethylamine → 4-(2-(Dimethylamino)ethoxy)benzeneboronic acid, pinacol ester

HRID 449145

Reaction equation

HRID 449145 reaction equation
Br[C:2]1[CH:13]=[CH:12][C:5]([O:6][CH2:7][CH2:8][N:9]([CH3:11])[CH3:10])=[CH:4][CH:3]=1.[CH3:14][C:15]1([CH3:36])[C:19]([CH3:21])([CH3:20])[O:18][B:17](C2C=CC(OC3C=CC=CC=3)=CC=2C)[O:16]1>>[CH3:10][N:9]([CH3:11])[CH2:8][CH2:7][O:6][C:5]1[CH:12]=[CH:13][C:2]([B:17]2[O:18][C:19]([CH3:21])([CH3:20])[C:15]([CH3:36])([CH3:14])[O:16]2)=[CH:3][CH:4]=1

Participants

3

Reactant 2

HCID 213877(2-(4-Bromophenoxy)ethyl)dimethylamineHCID 227364244,4,5,5-Tetramethyl-2-(2-methyl-4-phenoxyphenyl)-1,3,2-dioxaborolane

Product 1

HCID 425989244-(2-(Dimethylamino)ethoxy)benzeneboronic acid, pinacol ester

Procedure

Prepared from [2-(4-bromo-phenoxy)-ethyl]-dimethyl-amine according to general Method I for borylation described above for preparation of 4,4,5,5-tetramethyl-2-(2-methyl-4-phenoxy-phenyl)-[1,3,2]dioxaborolane.

Sources & evidence

ORD record
ord-0f273edde6754bd2ad727a970a3596cd
Source dataset
uspto-grants-2013_07
Patent number
US08481733B2

Linked notes

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