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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 449169Generated: October 26, 2026

Dopachrome → 5,6-Dihydroxyindole

https://huagongshe.com/reaction/449169

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDopachromeHCID 119399—
Reactant5,6-Dihydroxyindole-2-Carboxylic AcidHCID 119405—
Product5,6-DihydroxyindoleHCID 114683—

Reaction Steps

TRP-2 catalyzes the tautomerization of DOPAchrome to 5,6-dihydroxyindole-2-carboxylic acid (DHICA). In the absence of TRP-2, DOPAchrome undergoes spontaneous decarboxylation to form 5,6-dihydroxyindole (DHI).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08481762B2
Source datasetuspto-grants-2013_07
ORD IDord-2686d0c939a84ad186833e5a8cede20e
Source noteuspto-grants-2013_07