HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lamotrigine → 6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5-diamine;2-hydroxybutanedioate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lamotrigine | HCID 3878 | — |
| Reactant | Malic acid, disodium salt | HCID 8736 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5-diamine;2-hydroxybutanedioate | HCID 86632323 | — |
Reaction Steps
20 mg of lamotrigine was dissolved in 2 ml of methanol, 12 mg of malic acid sodium salt was added to the solution to form a single solution. The solution was then allowed to stand for several hours to effect the slow evaporation of solvent. The solids gathered were stored in screw cap vials for subsequent analysis.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08486927B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-1bfa01b5902049028c09a97c1103eb66 |
| Source note | uspto-grants-2013_07 |