3-Amino-5-hydroxypyrazole → HCID 178466985, compound

Reaction equation

[CH:1]([O:4][C:5]1[NH:9][N:8]=[C:7]([NH2:10])[CH:6]=1)(C)[CH3:2].NC1C=C(O)NN=1>>[CH2:1]([O:4][C:5]1[NH:9][N:8]=[C:7]([NH2:10])[CH:6]=1)[CH3:2]

Participants

Reactant 2

HCID 962213-Amino-5-hydroxypyrazole

HCID 1784587215-Isopropoxy-1H-pyrazol-3-amine

Product 1

HCID 178466985HCID 178466985, compound

Procedure

The title compound was prepared using a procedure similar to the one described for the synthesis of Intermediate 6, using 3-amino-5-hydroxypyrazole as the starting material. (400 MHz, CD3OD) □ ppm 4.85 (br s, 3H), 4.02 (m, 2H), 1.30 (t, J=8 Hz, 3H)

Sources & evidence

ORD record: ord-1784ee0ece604ac7a3b327479c99bd12
Source dataset: uspto-grants-2013_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08486966B2

Reaction notes

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