Methylamine ethanol → HCID 178485053, compound
Reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C@H:8]([O:22][CH2:23][CH2:24][NH:25][C:26](=[N:29][C:30]#[N:31])SC)[C@@H:9]2[CH2:14][CH2:13][CH2:12][N:11]([C:15]([O:17][C:18]([CH3:21])([CH3:20])[CH3:19])=[O:16])[CH2:10]2)[CH:5]=[CH:6][CH:7]=1.[CH3:32][NH2:33].CCO>>[Cl:1][C:2]1[CH:3]=[C:4]([C@H:8]([O:22][CH2:23][CH2:24][NH:25][C:26]([NH:33][CH3:32])=[N:29][C:30]#[N:31])[C@@H:9]2[CH2:14][CH2:13][CH2:12][N:11]([C:15]([O:17][C:18]([CH3:21])([CH3:20])[CH3:19])=[O:16])[CH2:10]2)[CH:5]=[CH:6][CH:7]=1Participants
3
Procedure
A 100 mL flask was charged with (R)-tert-butyl 3-((R)-(3-chlorophenyl)(2-((cyanoimino)(methylthio)methylamino)ethoxy)methyl)piperidine-1-carboxylate (2.2 g, 4.72 mmol) dissolved in 50 mL MeNH2/EtOH solution and stirred overnight. The mixture was concentrated in vacuo and used without any further purification.
Workup
- concentrationThe mixture was concentrated in vacuo
- customused without any further purification
Sources & evidence
- ORD record
- ord-88f27e0600fe417a924d0a329c4ebb2f