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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 45484Generated: October 25, 2026

4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole → 3-Phenyl-2-[3-(1H-pyrazol-4-yl)-phenyl]-propionitrile

https://huagongshe.com/reaction/45484

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazoleHCID 2774010—
Reactant2-(3-Bromo-phenyl)-3-phenyl-propionitrileHCID 59331981—
Product3-Phenyl-2-[3-(1H-pyrazol-4-yl)-phenyl]-propionitrileHCID 11300273—

Reaction Steps

2-(3-Bromo-phenyl)-3-phenyl-propionitrile was reacted with 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole following the procedure set out in Example 1 to give the title compound. (LC/MS: (PS-A) Rt 2.98 [M+H]+ 274).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08541461B2
Source datasetuspto-grants-2013_09
ORD IDord-c2e1cfad42664f9293490ffbe313de99
Source noteuspto-grants-2013_09