(4R,5S)-(+)-4-Methyl-5-phenyl-2-oxazolidinone → HCID 66890929, compound

HRID 456210Notes

Reaction equation

HRID 456210 reaction equation
[Br:1][C:2]1[CH:9]=[CH:8][C:7]([C:10]([F:13])([F:12])[F:11])=[CH:6][C:3]=1[CH2:4]Br.[CH3:14][C@@H:15]1[C@H:19]([C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[O:18][C:17](=[O:26])[NH:16]1>>[Br:1][C:2]1[CH:9]=[CH:8][C:7]([C:10]([F:13])([F:12])[F:11])=[CH:6][C:3]=1[CH2:4][N:16]1[C@H:15]([CH3:14])[C@H:19]([C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[O:18][C:17]1=[O:26]

Participants

3

Reactant 2

HCID 2733812(4R,5S)-(+)-4-Methyl-5-phenyl-2-oxazolidinoneHCID 27562491-Bromo-2-(bromomethyl)-4-(trifluoromethyl)benzene

Product 1

HCID 66890929HCID 66890929, compound

Procedure

Prepared according to the procedure described in Example 6, Step 3, using the following starting materials: 2-bromo-5-(trifluoromethyl)benzyl bromide and (4R,5S)-4-methyl-5-phenyl-2-oxazolidinone.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-4d49193ef7e047b7a7856bf0143f3013
Source dataset
uspto-grants-2013_07
Patent number
US08497381B2

Reaction notes

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