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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 456299Generated: October 27, 2026

Benzenebutanol → N-[4-(4-Phenylbutoxy)benzoyl]glycine

https://huagongshe.com/reaction/456299

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzenebutanolHCID 76889—
ReactantN-(4-Hydroxybenzoyl)glycine tert-butyl esterHCID 10682169—
ProductN-[4-(4-Phenylbutoxy)benzoyl]glycineHCID 6681262163%

Reaction Steps

The same reaction as in Example 1 (1b) was conducted using N-(4-hydroxybenzoyl)glycine tert-butyl ester (249 mg, 0.991 mmol) prepared in Example 1 (1a) and 4-phenylbutan-1-ol (200 μL, 1.30 mmol) to give 203 mg of the title compound (white powder, yield: 63%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08497397B2
Source datasetuspto-grants-2013_07
ORD IDord-568f649124d5415f9d3a269733b5a096
Source noteuspto-grants-2013_07