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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 456304Generated: October 23, 2026

2-Phenyl-1-propanol → N-[4-(2-Phenylpropoxy)benzoyl]glycine

https://huagongshe.com/en/reaction/456304

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Phenyl-1-propanolHCID 14295—
ReactantN-(4-Hydroxybenzoyl)glycine tert-butyl esterHCID 10682169—
ProductN-[4-(2-Phenylpropoxy)benzoyl]glycineHCID 6681248772%

Reaction Steps

The same reaction as in Example 1 (1b) was conducted using N-(4-hydroxybenzoyl)glycine tert-butyl ester (247 mg, 0.983 mmol) prepared in Example 1 (1a) and 2-phenylpropan-1-ol (185 μL, 1.32 mmol) to give 221 mg of the title compound (white powder, yield: 72%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08497397B2
Source datasetuspto-grants-2013_07
ORD IDord-732fcd1126af40698b572ccf3ab0506e
Source noteuspto-grants-2013_07