4-Benzylphenol → 3-{4-[3-(4-Benzyl-phenoxy)-propoxy]-3-methoxy-phenyl}-2-methoxy-propionic acid

HRID 459189

Reaction equation

Br[CH2:2][CH2:3][CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([CH2:12][CH:13]([O:17][CH3:18])[C:14]([OH:16])=[O:15])=[CH:8][C:7]=1[O:19][CH3:20].[CH2:21]([C:28]1[CH:33]=[CH:32][C:31]([OH:34])=[CH:30][CH:29]=1)[C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1>>[CH2:21]([C:28]1[CH:29]=[CH:30][C:31]([O:34][CH2:2][CH2:3][CH2:4][O:5][C:6]2[CH:11]=[CH:10][C:9]([CH2:12][CH:13]([O:17][CH3:18])[C:14]([OH:16])=[O:15])=[CH:8][C:7]=2[O:19][CH3:20])=[CH:32][CH:33]=1)[C:22]1[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=1

Participants

Reactant 2

HCID 75634-Benzylphenol

HCID 184436443-[4-(3-Bromo-propoxy)-3-methoxy-phenyl]-2-methoxy-propionic acid

Product 1

HCID 184436273-{4-[3-(4-Benzyl-phenoxy)-propoxy]-3-methoxy-phenyl}-2-methoxy-propionic acid

Procedure

The title compound was prepared from 3-[4-(3-Bromo-propoxy)-3-methoxy-phenyl]-2-methoxy-propionic acid and 4-benzylphenol following the Standard Procedure J. MS (ES) for C27H30O6 [M+NH4]+: 468, [M+Na]+: 473.

Sources & evidence

ORD record: ord-178eb45949ed472b9c25a3034b907d8e
Source dataset: uspto-grants-2007_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07192982B2

Linked notes

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