p-(4-(Trifluoromethyl)phenoxy)phenol → 2-Methoxy-3-(3-methoxy-4-{3-[4-(4-trifluoromethyl-phenoxy)-phenoxy]-propoxy}-phenyl)-propionic acid
Reaction equation
Br[CH2:2][CH2:3][CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([CH2:12][CH:13]([O:17][CH3:18])[C:14]([OH:16])=[O:15])=[CH:8][C:7]=1[O:19][CH3:20].[F:21][C:22]([F:38])([F:37])[C:23]1[CH:36]=[CH:35][C:26]([O:27][C:28]2[CH:33]=[CH:32][C:31]([OH:34])=[CH:30][CH:29]=2)=[CH:25][CH:24]=1>>[CH3:18][O:17][CH:13]([CH2:12][C:9]1[CH:10]=[CH:11][C:6]([O:5][CH2:4][CH2:3][CH2:2][O:34][C:31]2[CH:32]=[CH:33][C:28]([O:27][C:26]3[CH:35]=[CH:36][C:23]([C:22]([F:21])([F:37])[F:38])=[CH:24][CH:25]=3)=[CH:29][CH:30]=2)=[C:7]([O:19][CH3:20])[CH:8]=1)[C:14]([OH:16])=[O:15]Participants
3
Procedure
The title compound was prepared from 3-[4-(3-Bromo-propoxy)-3-methoxy-phenyl]-2-methoxy-propionic acid (Example 175, Step B) and 4-(4-Trifluoromethyl-phenoxy)-phenol following the Standard Procedure J. MS (ES) for C27H27F3O7 [M+Na]+: 543.
Sources & evidence
- ORD record
- ord-25fa521423884e838e888c7a4506289c
- Source dataset