HCID 18443682, compound → 4-(Benzyloxy)-2-chlorobenzaldehyde
Reaction equation
[CH2:1]([O:8][C:9]1[CH:14]=[CH:13][C:12]([CH2:15][OH:16])=[C:11]([Cl:17])[CH:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>ClCCl.O=[Mn]=O>[CH2:1]([O:8][C:9]1[CH:14]=[CH:13][C:12]([CH:15]=[O:16])=[C:11]([Cl:17])[CH:10]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1Participants
4
Reactant 1
Product 1
Reagents, catalysts & solvents 2
Procedure
To a solution of (4-Benzyloxy-2-chloro-phenyl)-methanol in dichloromethane, MnO2 (10 eq) were added and the mixture reaction stirred overnight. Filtered through a pad of celite and purified by chromatography in silica gel to give the title product.
Workup
- customthe mixture reaction
- filtrationFiltered through a pad of celite
- custompurified by chromatography in silica gel
Sources & evidence
- ORD record
- ord-4d2a72e663aa4d1c8863e6081abd266f
- Source dataset
- uspto-grants-2007_03
- Patent number
- US07192982B2
Reaction notes
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