HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → (2S)-2-Methoxy-3-(4-{3-[4-(3-phenyl-propionyl)-phenoxy]-propoxy}-phenyl)-propionic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 1-(4-Hydroxyphenyl)-3-phenylpropan-1-one | HCID 14416163 | — |
| Reactant | (2S)-3-[4-(3-Bromopropoxy)-phenyl]-2-methoxy-propionic acid ethyl ester | HCID 58822859 | — |
| Product | (2S)-2-Methoxy-3-(4-{3-[4-(3-phenyl-propionyl)-phenoxy]-propoxy}-phenyl)-propionic acid | HCID 10204975 | — |
Reaction Steps
(2S)-3-[4-(3-Bromo-propoxy)-phenyl]-2-methoxy-propionic acid ethyl ester from Example 173, Step A was treated with 1-(4-Hydroxy-phenyl)-3-phenyl-propan-1-one from Step A under the Standard Procedure J. The compound thus obtained was allowed to react under Standard hydrolysis procedure C (NaOH) to give the title compound. MS(ES) for C28H30O6 [M+NH4]+: 485 [M+H]+: 463.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07192982B2 |
| Source dataset | uspto-grants-2007_03 |
| ORD ID | ord-c7bb5812cc4748d6a8e2dd908bf45f85 |
| Source note | uspto-grants-2007_03 |