HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Morpholinophenol → (2S)-2-Methoxy-3-{4-[2-(3-morpholin-4-yl-phenoxy)-ethoxy]-phenyl}-propionic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Morpholinophenol | HCID 141343 | — |
| Reactant | (2S)-3-[4-(2-bromo-ethoxy)-phenyl]2-methoxy-propionic acid ethyl ester | HCID 58822865 | — |
| Reactant | (2S)-2-methoxy-3-[4-(3-phenoxy propoxy)-phenyl]-propionic acid | HCID 58822897 | — |
| Product | (2S)-2-Methoxy-3-{4-[2-(3-morpholin-4-yl-phenoxy)-ethoxy]-phenyl}-propionic acid | HCID 58822906 | — |
Reaction Steps
The title compound was prepared from (2S)-3-[4-(2-bromo-ethoxy)-phenyl]-2-methoxy-propionic acid ethyl ester (Example 283, Step 2) and 3-morpholin-4-yl-phenol via the same procedure used for the preparation of (2S)-2-methoxy-3-[4-(3-phenoxy-propoxy)-phenyl]-propionic acid (Example 285, Step 1), to produce a yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07192982B2 |
| Source dataset | uspto-grants-2007_03 |
| ORD ID | ord-3044bd01d57d4ec0a6e9ca17df8a9fb5 |
| Source note | uspto-grants-2007_03 |