Reaction equation
[CH2:1]([O:8][C:9]1[CH:10]=[C:11]([CH:14]=[CH:15][CH:16]=1)[CH:12]=[O:13])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:17]([O:19][CH2:20][C:21]([O:23][CH2:24][CH3:25])=[O:22])[CH3:18].COC(=O)C(OC)C(C1C=CC=C(OCC2C=CC=CC=2)C=1)O>>[CH2:24]([O:23][C:21](=[O:22])[CH:20]([O:19][CH2:17][CH3:18])[CH:12]([C:11]1[CH:14]=[CH:15][CH:16]=[C:9]([O:8][CH2:1][C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)[CH:10]=1)[OH:13])[CH3:25]Participants
4
Procedure
The title compound was prepared from 3-benzyloxy-benzaldehyde and ethyl ethoxyacetate via the same procedure used for the preparation of 3-(3-benzyloxy-phenyl)-3-hydroxy-2-methoxy-propionic acid methyl ester (Example 291, Step 1) to afford the title compound as a colorless oil.
Sources & evidence
- ORD record
- ord-17d35e39a6b042eea559149505d819f0
- Source dataset
- uspto-grants-2007_03
- Patent number
- US07192982B2
Linked notes
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