Butanoic acid, 2-bromo-, ethyl ester → HCID 178438252, compound

Reaction equation

[CH2:1]1[CH2:6][CH2:5][CH:4]([NH:7][C:8]([NH2:10])=[S:9])[CH2:3][CH2:2]1.Br[CH:12]([CH2:18][CH3:19])[C:13](OCC)=[O:14]>>[CH:4]1([NH:7][C:8]2[S:9][CH:12]([CH2:18][CH3:19])[C:13](=[O:14])[N:10]=2)[CH2:5][CH2:6][CH2:1][CH2:2][CH2:3]1

Participants

Reactant 2

HCID 79039Butanoic acid, 2-bromo-, ethyl ester

HCID 1471603Cyclohexylthiourea

Product 1

HCID 178438252HCID 178438252, compound

Procedure

Synthesis was performed from n-cyclohexylthiourea and ethyl 2-bromobutyrate according to Method C. Gave 201 mg (75%).

Workup

customSynthesis
customGave 201 mg (75%)

Sources & evidence

ORD record: ord-240c5d7a97db48028804ece083788aab
Source dataset: uspto-grants-2013_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08541592B2

Reaction notes

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