3-Methoxypropylamine → N-(3-Methoxypropyl)-6-[[2-(piperidin-1-yl)-1-phenyl-1H-benzimidazol-6-yl]oxy]Hexanamide
Reaction equation
CO[C:3](=[O:31])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][O:9][C:10]1[CH:11]=[CH:12][C:13]2[N:17]=[C:16]([N:18]3[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]3)[N:15]([C:24]3[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=3)[C:14]=2[CH:30]=1.[CH3:32][O:33][CH2:34][CH2:35][CH2:36][NH2:37]>>[CH3:32][O:33][CH2:34][CH2:35][CH2:36][NH:37][C:3](=[O:31])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][O:9][C:10]1[CH:11]=[CH:12][C:13]2[N:17]=[C:16]([N:18]3[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]3)[N:15]([C:24]3[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=3)[C:14]=2[CH:30]=1Participants
3
Procedure
100 mg of 6-[[2-(piperidin-1-yl)-1-phenyl-1H-benzimidazol-6-yl]oxy]hexanoic acid methyl ester was reacted with 3-methoxypropylamine according to general operating instructions 4. 47 mg was obtained.
Workup
- custom47 mg was obtained