HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 1-Phenyl-2-chloro-cyclohex-3-ene-carboxylic-acid-ethyl-ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 1-Phenyl-2-acetoxy-cyclohex-3-ene-1-carboxylic acid-ethyl-ester | HCID 21394564 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 1-Phenyl-2-chloro-cyclohex-3-ene-carboxylic-acid-ethyl-ester | HCID 21394560 | — |
Reaction Steps
200 g of 1-phenyl-2-acetoxy-cyclohex-3-ene-1-carboxylic acid-ethyl-ester are dissolved in 1 liter of 96% ethanol. The solution is charged with 190 g of HCl gas and heated under reflux for 2 hrs. The solvent is removed and the residue directly fractionated in the vacuum. b.p.°,1 130° C. Yield: 169 g.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04061635 |
| Source dataset | uspto-grants-1977_12 |
| ORD ID | ord-564c88fd42a544399a84ff288f33291c |
| Source note | uspto-grants-1977_12 |