N,N'-Dibutylthiourea → 3-Butyl-2-butylimino-4-(2,4-dichloro-5-sulfamoylphenyl)-1,3-thiazolidine-4-ol-hydrobromide

HRID 460823

Reaction equation

HRID 460823 reaction equation
[Br:1][CH2:2][C:3]([C:5]1[CH:10]=[C:9]([S:11](=[O:14])(=[O:13])[NH2:12])[C:8]([Cl:15])=[CH:7][C:6]=1[Cl:16])=[O:4].[CH2:17]([NH:21][C:22]([NH:24][CH2:25][CH2:26][CH2:27][CH3:28])=[S:23])[CH2:18][CH2:19][CH3:20]>>[BrH:1].[CH2:25]([N:24]1[C:3]([C:5]2[CH:10]=[C:9]([S:11](=[O:14])(=[O:13])[NH2:12])[C:8]([Cl:15])=[CH:7][C:6]=2[Cl:16])([OH:4])[CH2:2][S:23][C:22]1=[N:21][CH2:17][CH2:18][CH2:19][CH3:20])[CH2:26][CH2:27][CH3:28]

Participants

3

Reactant 2

HCID 2723622N,N'-DibutylthioureaHCID 227564292-Bromo-2',4'-dichloro-5'-sulfamoylacetophenone

Product 1

HCID 213947953-Butyl-2-butylimino-4-(2,4-dichloro-5-sulfamoylphenyl)-1,3-thiazolidine-4-ol-hydrobromide

Procedure

was obtained in a manner analogous to the method described in Example 10 from 3.5 g of 2-bromo-2',4'-dichloro-5'-sulfamoylacetophenone and 1.9 g of 1.3-dibutyl-thiourea. M.p. 194° C (decomposition).

Workup

  1. customwas obtained in a manner analogous to the method

Sources & evidence

ORD record
ord-4d419e4c8c0749458abd3c69f57ab84a
Source dataset
uspto-grants-1977_12
Patent number
US04061647

Linked notes

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