Reaction equation
[N:1]1([CH2:7][CH2:8][NH:9][C:10]([NH2:12])=[S:11])[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1.Br[CH:14]([CH:20]([CH3:22])[CH3:21])[C:15](OCC)=[O:16]>>[CH:20]([CH:14]1[S:11][C:10]([NH:9][CH2:8][CH2:7][N:1]2[CH2:2][CH2:3][O:4][CH2:5][CH2:6]2)=[N:12][C:15]1=[O:16])([CH3:22])[CH3:21]Participants
3
Procedure
Synthesis was performed from N-(2-morpholin-4-ylethyl)thiourea and ethyl 2-bromo-3-methylbutanoate according to Method C.
Workup
- customSynthesis
Sources & evidence
- ORD record
- ord-542bbc26676b4039bf330b89f20f8701
- Source dataset
- uspto-grants-2013_09
- Patent number
- US08541592B2
Linked notes
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