beta-Aminobeta-ethoxyacrylic acid ethyl ester → 3-Amino-1-(3-nitrobenzyl)-pyrazol-5-one

HRID 460891

Reaction equation

HRID 460891 reaction equation
C([O:3][C:4](=O)[CH:5]=[C:6]([NH2:10])OCC)C.[N+:12]([C:15]1[CH:16]=[C:17]([CH:21]=[CH:22][CH:23]=1)[CH2:18][NH:19][NH2:20])([O-:14])=[O:13]>>[NH2:10][C:6]1[NH:20][N:19]([CH2:18][C:17]2[CH:21]=[CH:22][CH:23]=[C:15]([N+:12]([O-:14])=[O:13])[CH:16]=2)[C:4](=[O:3])[CH:5]=1

Participants

3

Reactant 2

HCID 278451beta-Aminobeta-ethoxyacrylic acid ethyl esterHCID 20511322(3-Nitrobenzyl)hydrazine

Product 1

HCID 203671933-Amino-1-(3-nitrobenzyl)-pyrazol-5-one

Procedure

17.5 g of β-amino-β-ethoxyacrylic acid ethyl ester and 16.7 g of 3-nitrobenzylhydrazine, analogously to the procedure described in Example 1 yield 12.3 g of the compound identified above as yellow crystals of melting point 163°, corresponding to 52% of theory.

Sources & evidence

ORD record
ord-ceddf81bb8074af4936d1824326f91d0
Source dataset
uspto-grants-1977_12
Patent number
US04061653

Linked notes

Loading…