beta-Aminobeta-ethoxyacrylic acid ethyl ester → HCID 20367323, compound

Reaction equation

C([O:3][C:4](=O)[CH:5]=[C:6]([NH2:10])OCC)C.[Cl:12][C:13]1[CH:21]=[CH:20][CH:19]=[C:18]([Cl:22])[C:14]=1[CH2:15][NH:16][NH2:17]>>[NH2:10][C:6]1[NH:17][N:16]([CH2:15][C:14]2[C:13]([Cl:12])=[CH:21][CH:20]=[CH:19][C:18]=2[Cl:22])[C:4](=[O:3])[CH:5]=1

Participants

Reactant 2

HCID 278451beta-Aminobeta-ethoxyacrylic acid ethyl ester

HCID 46250371-(2,6-Dichlorobenzyl)hydrazine

Product 1

HCID 20367323HCID 20367323, compound

Procedure

35 g of β-amino-β-ethoxyacrylic acid ethyl ester and 38 g of 2,6-dichlorobenzylhydrazine when reacted as described in Example 45, yield 24 g of the compound identified above as colorless crystals, corresponding to 46% of theory, of melting point 225°.

Sources & evidence

ORD record: ord-03837172c6ef4d9f91f28d9c989ab8ae
Source dataset: uspto-grants-1977_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04061653

Reaction notes

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