HCID 462453, compound → HCID 21395224, compound

Reaction equation

Cl[CH2:2][CH2:3][N:4]1[CH2:9][CH2:8][CH:7]([NH:10][C:11](=[O:20])[C:12]2[C:17]([Cl:18])=[CH:16][CH:15]=[CH:14][C:13]=2[Cl:19])[CH2:6][CH2:5]1.[CH3:21][C:22]1[CH:35]=[CH:34][C:25]([CH2:26][NH:27][C:28]2[CH:33]=[CH:32][CH:31]=[CH:30][N:29]=2)=[CH:24][CH:23]=1>>[Cl:19][C:13]1[CH:14]=[CH:15][CH:16]=[C:17]([Cl:18])[C:12]=1[C:11]([NH:10][CH:7]1[CH2:8][CH2:9][N:4]([CH2:3][CH2:2][N:27]([CH2:26][C:25]2[CH:24]=[CH:23][C:22]([CH3:21])=[CH:35][CH:34]=2)[C:28]2[CH:33]=[CH:32][CH:31]=[CH:30][N:29]=2)[CH2:5][CH2:6]1)=[O:20]

Participants

Reactant 2

HCID 462453HCID 462453, compound

HCID 21395222HCID 21395222, compound

Product 1

HCID 21395224HCID 21395224, compound

Procedure

The title compound is prepared in a manner similar to Example 11 using 1-(2-chloroethyl)-4-(2,6-dichlorobenzamido)piperidine and 2-(p-methylbenzyl)aminopyridine.

Sources & evidence

ORD record: ord-933b539e8deb4d4f8d364088a5d04464
Source dataset: uspto-grants-1977_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04061758

Reaction notes

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