p-(3-Phenylpropoxy)-alpha-methylbenzylamine hydrochloride → HCID 178463296, compound
Reaction equation
[ClH:1].[C:2]1([CH2:8][CH2:9][CH2:10][O:11][C:12]2[CH:20]=[CH:19][C:15]([CH:16]([NH2:18])[CH3:17])=[CH:14][CH:13]=2)[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl.CC(N=[C:39]1[CH2:45][CH2:44][CH2:43][CH2:42][CH2:41][NH:40]1)C1C=CC(CCC2C=CC=CC=2)=CC=1>>[ClH:1].[CH3:17][CH:16]([N:18]=[C:39]1[CH2:45][CH2:44][CH2:43][CH2:42][CH2:41][NH:40]1)[C:15]1[CH:14]=[CH:13][C:12]([O:11][CH2:10][CH2:9][CH2:8][C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)=[CH:20][CH:19]=1Participants
3
Procedure
Substituting this amine for the α-methyl-p-phenethylbenzylamine of Example 7 results in the formation of hexahydro-2-[α-methyl-p-(3-phenylpropoxy)benzylimino]-azepine hydrochloride, having a M.P. of 202°-5° C.
Sources & evidence
- ORD record
- ord-23b4866311e4469088230a68ed421db9
- Source dataset
- uspto-grants-1977_12
- Patent number
- US04061746