Thionyl Chloride → 3-Sulfamoylbenzoyl chloride

HRID 461162

Reaction equation

[S:1]([C:5]1[CH:6]=[C:7]([CH:11]=[CH:12][CH:13]=1)[C:8](O)=[O:9])(=[O:4])(=[O:3])[NH2:2].S(Cl)([Cl:16])=O>>[S:1]([C:5]1[CH:6]=[C:7]([CH:11]=[CH:12][CH:13]=1)[C:8]([Cl:16])=[O:9])(=[O:4])(=[O:3])[NH2:2]

Participants

Reactant 2

HCID 24386Thionyl Chloride

HCID 2293523-Sulfamoylbenzoic acid

Product 1

HCID 188018833-Sulfamoylbenzoyl chloride

Procedure

10 g of ground 3-sulfamoylbenzoic acid were reacted as prescribed in Example 70b), the thionyl chloride was distilled off and the residue was crystallized under a mixture of petroleum ether and diethyl ether (1:1). Melting point: 123° C.

Workup

distillationwas distilled off
customthe residue was crystallized under a mixture of petroleum ether and diethyl ether (1:1)

Sources & evidence

ORD record: ord-fd25773f3f24442092591b5bfa79d79e
Source dataset: uspto-grants-1977_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04061761

Linked notes

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