Water → HCID 24708775, compound

HRID 461519

Reaction equation

HRID 461519 reaction equation
[OH:1][C:2]1[CH:12]=[CH:11][C:5]([CH2:6][CH2:7][C:8](=[O:10])[CH3:9])=[CH:4][CH:3]=1.[OH-].[K+].[CH2:15](Br)[CH:16]=[CH2:17].O>C(O)C>[CH2:17]([O:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:6][CH2:7][C:8](=[O:10])[CH3:9])=[CH:11][CH:12]=1)[CH:16]=[CH2:15]

Participants

6

Reactant 4

HCID 962WaterHCID 7841Allyl bromideHCID 14797Potassium HydroxideHCID 216484-(4'-Hydroxyphenyl)-2-butanone

Product 1

HCID 24708775HCID 24708775, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

p-Hydroxy benzylacetone (1.5 g.), KOH (6 g.) and allyl bromide (1.2 g.) were stirred in ethanol (50 ml) overnight. Water was added and the mixture extracted with ether, which was evaporated to give the compound (1.6 g.) as an oil purified by column chromatography.

Workup

  1. extractionthe mixture extracted with ether, which
  2. customwas evaporated
  3. customto give the compound (1.6 g.) as an oil
  4. custompurified by column chromatography

Sources & evidence

ORD record
ord-67502816a83c4a06a3fe4d307df71c29
Source dataset
uspto-grants-1977_12
Patent number
US04062978

Linked notes

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