1-Aminohydantoin → HCID 86735284, compound

HRID 461532

Reaction equation

HRID 461532 reaction equation
[N:1]([CH:4]([C:10]1[S:11][CH:12]=[CH:13][CH:14]=1)[C:5]([O:7][CH2:8][CH3:9])=[O:6])=[C:2]=[O:3].[NH2:15][N:16]1[CH2:20][C:19](=[O:21])[NH:18][C:17]1=[O:22]>O1CCOCC1>[O:22]=[C:17]1[NH:18][C:19](=[O:21])[CH2:20][N:16]1[NH:15][C:2]([NH:1][CH:4]([C:10]1[S:11][CH:12]=[CH:13][CH:14]=1)[C:5]([O:7][CH2:8][CH3:9])=[O:6])=[O:3]

Participants

4

Reactant 2

HCID 728231-AminohydantoinHCID 54068691alpha-Isocyanato-2-thiopheneacetic acid, ethyl ester

Product 1

HCID 86735284HCID 86735284, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

By reacting 10.60 g. of DL-α-isocyanato-2-thiopheneacetic acid, ethyl ester with 5.75 g. of 1-amino-2,4-dioxoimidazolidine in 250 ml. of dioxane according to the procedure of Example 5, 15.6 g. of DL-α-[[[(2,4-dioxo-1-imidazolidinyl)-amino]carbonyl]amino]-2-thiopheneacetic acid, ethyl ester is obtained, m.p. 151°-155°.

Sources & evidence

ORD record
ord-d8b1c81ab80b4eae9fdbc3ce052bd370
Source dataset
uspto-grants-1977_12
Patent number
US04063019

Linked notes

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