Water → HCID 178511811, compound
Reaction equation
[NH2:1][C@H:2]([C:9]([OH:11])=[O:10])[CH2:3][C:4]1[N:8]=[CH:7][NH:6][CH:5]=1.[OH:12][P:13]([F:16])([OH:15])=[O:14].O>CO.C(O)C>[P:13]([F:16])([OH:15])([OH:14])=[O:12].[NH2:1][C@H:2]([C:9]([OH:11])=[O:10])[CH2:3][C:4]1[N:8]=[CH:7][NH:6][CH:5]=1Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
L-histidine monofluorophosphate was prepared by combining 31 gm. of free-base L-histidine with 20 gm. of monofluorophosphoric acid in about 75 ml. of water. A clear syrup resulted. The syrup was poured into 750 ml. of a methanol-ethanol mixture. The precipitate (L-histidine monofluorophosphate) was collected and vacuum dried in a desiccator.
Workup
- customA clear syrup resulted
- additionThe syrup was poured into 750 ml
- customThe precipitate (L-histidine monofluorophosphate) was collected
- customvacuum dried in a desiccator
Sources & evidence
- ORD record
- ord-17e90312b2714341854be25add764976
- Source dataset
- uspto-grants-1977_12
- Patent number
- US04064138
Reaction notes
Loading…