Tert-Butylamine → 2-(2-t-Butylamino-5-thiadiazolyl)-1-methyl-5-nitroimidazole

Participants

Reaction Steps

The preparation of the above compound is accomplished essentially by the procedure described for the 2-cyclohexylamino derivative (Example 38), an equivalent of t-butylamine replacing the cyclohexylamine. Recrystallization of the crude product from a mixture of ethyl acetate and acetone gives the pure compound melting at 249°-251° C.

Provenance & Evidence