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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 4630Generated: October 25, 2026

Phosphorus oxychloride → N-Butyl-N'-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]1,3,4-thiadiazole-2,5-diamine

https://huagongshe.com/reaction/4630

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhosphorus oxychlorideHCID 24813—
ReactantN-butyl-2-[[3-[3-(1-piperidinylmethyl)phenoxy]propyl]aminothioxomethyl]hydrazine carboxamideHCID 13657339—
ProductN-Butyl-N'-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]1,3,4-thiadiazole-2,5-diamineHCID 13657367—

Reaction Steps

The compound is prepared by a method analogous to that of Example 40 from N-butyl-2-[[3-[3-(1-piperidinylmethyl)phenoxy]propyl]aminothioxomethyl]hydrazine carboxamide and phosphorus oxychloride. The analytical values are summarized in Table III.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04727081
Source datasetuspto-grants-1988_02
ORD IDord-d78e7903616a47b5a9621809086959ae
Source noteuspto-grants-1988_02