HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Toluenesulfonic acid → Tampramine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Toluenesulfonic acid | HCID 6101 | — |
| Reactant | [2-[(3-Amino-2-pyridinyl)[3-(dimethylamino)propyl]amino]phenyl]phenylmethanone | HCID 53769600 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | Tampramine | HCID 54961 | — |
Reaction Steps
[2-[[3-(Dimethylamino)propyl](3-amino-2-pyridinyl)amino]phenyl]phenylmethanone from Example 21a is refluxed in excess acetic acid or in toluene solution containing a catalytic amount of p-toluene sulfonic acid to give a solution of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04518603 |
| Source dataset | uspto-grants-1985_05 |
| ORD ID | ord-e98347ba6d34436bae05b0ae107a8077 |
| Source note | uspto-grants-1985_05 |