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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 4632Generated: October 25, 2026

Phosphorus oxychloride → N-Methyl-N'-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]1,3,4-oxadiazole-2,5-diamine

https://huagongshe.com/reaction/4632

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhosphorus oxychlorideHCID 24813—
ReactantN-Methyl-N'-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]1,2-hydrazine dicarboxamideHCID 13657347—
ProductN-Methyl-N'-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]1,3,4-oxadiazole-2,5-diamineHCID 13657370—

Reaction Steps

The compound is prepared by a method analogous to that of Example 40 from N-methyl-N'-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]-1,2-hydrazine dicarboxamide and phosphorus oxychloride. The analytical values are summarized in Table III.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04727081
Source datasetuspto-grants-1988_02
ORD IDord-971b8e9f32ef4c168ef57c971277054d
Source noteuspto-grants-1988_02