Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 4635Generated: October 24, 2026

Phosphorus oxychloride → 2-(4-Chlorophenylamino)-5-[3-[3-(piperidinomethyl)phenoxy]propylamino]-1,3,4-oxadiazole

https://huagongshe.com/en/reaction/4635

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhosphorus oxychlorideHCID 24813—
ReactantN-4-chlorophenyl-N'-[3-[3-(1piperidinylmethyl)phenoxy]propyl]-1,2-hydrazine dicarboxamideHCID 13657353—
Product2-(4-Chlorophenylamino)-5-[3-[3-(piperidinomethyl)phenoxy]propylamino]-1,3,4-oxadiazoleHCID 558688—

Reaction Steps

The compound is prepared by a method analogous to that of Example 40 from N-4-chlorophenyl-N'-[3-[3-(1piperidinylmethyl)phenoxy]propyl]-1,2-hydrazine dicarboxamide and phosphorus oxychloride. The analytical values are summarized in Table III.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04727081
Source datasetuspto-grants-1988_02
ORD IDord-f89ec35a77d24dec965a72076856b42d
Source noteuspto-grants-1988_02