HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloro-1,2-dinitrobenzene → ethyl P-methyl-2-nitro-5-chlorophenylphosphinate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloro-1,2-dinitrobenzene | HCID 33097 | — |
| Reactant | Diethyl methylphosphonite | HCID 85063 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | ethyl P-methyl-2-nitro-5-chlorophenylphosphinate | HCID 53860251 | — |
Reaction Steps
To 4-chloro-1,2-dinitrobenzene (13.2 g, 65.0 mmol) dissolved in acetonitrile (150 ml) is added, dropwise, diethyl methylphosphonite (16.0 g, 117.6 mmol). The mixture is stirred at RT for 20 hours, after which it is concentrated. The crude product is purified by column chromatography (developing with 50% ethyl acetate/hexane) to yield ethyl P-methyl-2-nitro-5-chlorophenylphosphinate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04520197 |
| Source dataset | uspto-grants-1985_05 |
| ORD ID | ord-cd5e6dca7b5048fab9a1583e2647bcfa |
| Source note | uspto-grants-1985_05 |