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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 463563Generated: October 24, 2026

4-Chlorobutanoic acid → Gamma-Butyrolactone

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Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chlorobutanoic acidHCID 12300—
ReactantPotassium HydroxideHCID 14797—
ProductGamma-ButyrolactoneHCID 7302—
ProductCyclopropanecarboxylic acidHCID 15655—

Reaction Steps

It is known to condense the ethyl ester of 4-chlorobutyric acid with aqueous potassium hydroxide on pumice. There is obtained thereby in moderate yield the ethyl ester of cyclopropane carboxylic acid besides the free acid and γ-butyrolactone (Rambaud, BL. [5] (1938), pages 1552, 1564).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04520209
Source datasetuspto-grants-1985_05
ORD IDord-036e0e2f002e418d8ac86ca239b78336
Source noteuspto-grants-1985_05