Methyl iodide → 5-Methoxymethylbenzo[b]furan
Reaction equation
[OH-].[K+].[OH:3][CH2:4][C:5]1[CH:13]=[CH:12][C:8]2[O:9][CH:10]=[CH:11][C:7]=2[CH:6]=1.[CH3:14]I>CS(C)=O>[CH3:14][O:3][CH2:4][C:5]1[CH:13]=[CH:12][C:8]2[O:9][CH:10]=[CH:11][C:7]=2[CH:6]=1Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
To a stirred mixture of powdered KOH in dimethylsulfoxide is added 5-hydroxymethylbenzo[b]furan in dimethylsulfoxide. Then methyl iodide is added dropwise at ambient temperature over several minutes to provide the title compound.
Sources & evidence
- ORD record
- ord-e005b215c04741cdbcd123a081bde0c3
- Source dataset
- uspto-grants-1985_10
- Patent number
- US04544667
Reaction notes
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