2-Amino-5-bromo-1,3,4-thiadiazole → N-[3-[3-[(Dimethylamino)methyl]phenoxy]propyl]-1,3,4-thiadiazole-2,5-diamin

HRID 4639

Reaction equation

HRID 4639 reaction equation
[CH3:1][N:2]([CH2:4][C:5]1[CH:6]=[C:7]([CH:13]=[CH:14][CH:15]=1)[O:8][CH2:9][CH2:10][CH2:11][NH2:12])[CH3:3].Br[C:17]1[S:21][C:20]([NH2:22])=[N:19][N:18]=1>>[CH3:1][N:2]([CH2:4][C:5]1[CH:6]=[C:7]([CH:13]=[CH:14][CH:15]=1)[O:8][CH2:9][CH2:10][CH2:11][NH:12][C:17]1[S:21][C:20]([NH2:22])=[N:19][N:18]=1)[CH3:3]

Participants

3

Reactant 2

HCID 36508832-Amino-5-bromo-1,3,4-thiadiazoleHCID 129139503-(3-Aminopropoxy)-N,N-dimethylbenzenemethanamine

Product 1

HCID 20151482N-[3-[3-[(Dimethylamino)methyl]phenoxy]propyl]-1,3,4-thiadiazole-2,5-diamin

Procedure

The compound is prepared by a method analogous to that of Example 51 from 3-[3-[(dimethylamino)methyl]phenoxy]-1-propanamine and 5-bromo-1,3,4-thiadiazole-2amine.

Sources & evidence

ORD record
ord-5aa43ab20cb0403ab1a162f7107fcb04
Source dataset
uspto-grants-1988_02
Patent number
US04727081

Linked notes

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