2-Amino-5-bromo-1,3,4-thiadiazole → N-[3-[3-(1-Piperidinylmethyl)phenoxy]propyl]-1,3,4-thiadiazole-2,5-diamine

HRID 4641

Reaction equation

HRID 4641 reaction equation
[N:1]1([CH2:7][C:8]2[CH:9]=[C:10]([CH:16]=[CH:17][CH:18]=2)[O:11][CH2:12][CH2:13][CH2:14][NH2:15])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.Br[C:20]1[S:24][C:23]([NH2:25])=[N:22][N:21]=1>>[N:1]1([CH2:7][C:8]2[CH:9]=[C:10]([CH:16]=[CH:17][CH:18]=2)[O:11][CH2:12][CH2:13][CH2:14][NH:15][C:20]2[S:24][C:23]([NH2:25])=[N:22][N:21]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 36508832-Amino-5-bromo-1,3,4-thiadiazoleHCID 102205613-(3-(Piperidin-1-ylmethyl)phenoxy)propan-1-amine

Product 1

HCID 13541111N-[3-[3-(1-Piperidinylmethyl)phenoxy]propyl]-1,3,4-thiadiazole-2,5-diamine

Procedure

The compound is prepared by a method analogous to that of Example 51 from 3-[3-(1-piperidinylmethyl)phenoxy]-1-propanamine and 5-bromo-1,3,4-thiadiazole-2-amine. The product obtained is identical to the substance described in Example 50.

Workup

  1. customThe product obtained

Sources & evidence

ORD record
ord-be78e38a63a04e01bcbdccac00953061
Source dataset
uspto-grants-1988_02
Patent number
US04727081

Linked notes

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