2-Amino-5-bromo-1,3,4-thiadiazole → N-[4-[3-(1-Piperidinylmethyl)phenoxy]butyl]-1,3,4-thiadiazole-2,5-diamine

HRID 4647

Reaction equation

HRID 4647 reaction equation
[N:1]1([CH2:7][C:8]2[CH:9]=[C:10]([CH:17]=[CH:18][CH:19]=2)[O:11][CH2:12][CH2:13][CH2:14][CH2:15][NH2:16])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.Br[C:21]1[S:25][C:24]([NH2:26])=[N:23][N:22]=1>>[N:1]1([CH2:7][C:8]2[CH:9]=[C:10]([CH:17]=[CH:18][CH:19]=2)[O:11][CH2:12][CH2:13][CH2:14][CH2:15][NH:16][C:21]2[S:25][C:24]([NH2:26])=[N:23][N:22]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 36508832-Amino-5-bromo-1,3,4-thiadiazoleHCID 137906124-(3-Piperidinomethylphenoxy)butaneamine

Product 1

HCID 20142397N-[4-[3-(1-Piperidinylmethyl)phenoxy]butyl]-1,3,4-thiadiazole-2,5-diamine

Procedure

The compound is prepared by a method analogous to that of Example 51 from 4-[3-(1-piperidinylmethyl)phenoxy]1-butanamine and 5-bromo-1,3,4-thiadiazole-2-amine.

Sources & evidence

ORD record
ord-424437dd939048d781b5e36f7d3f50fa
Source dataset
uspto-grants-1988_02
Patent number
US04727081

Linked notes

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